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. Author manuscript; available in PMC: 2022 Dec 24.
Published in final edited form as: Sci Immunol. 2022 Jun 24;7(72):eabo5407. doi: 10.1126/sciimmunol.abo5407

Figure 2. Altered immune homeostasis in Foxp3 ΔE2 mice at 8 weeks of age.

Figure 2.

(A) Size and cellularity of lymph nodes and spleen in WT and Foxp3 ΔE2 mice. (B) Flow cytometric analysis of B220+ B cells, CD4+ and CD8+ T cells in peripheral (pLN) and spleen of WT and Foxp3 ΔE2 mice. (C) Expression of CD62L and CD44 in CD4+ T cells of WT and Foxp3 ΔE2 mice. (D) Expression of IL-4 and IFN-γ in CD4+ T cells ex vivo from pLN of WT and Foxp3 ΔE2 mice. (E) Expression of IL-17 in CD4+ T cells ex vivo from pLN of WT and Foxp3 ΔE2 mice. Data represent mean ± SEM from one of ≥ 2 experiments. ns: not significant; *: p < 0.05; **: p < 0.01; ***: p < 0.001 by multiple t-tests (A - D) or two-tailed t-test (E).