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Pathways activated by Cordyceps sinensis (CS) and cordycepin in normal mouse Leydig cells and MA-10 cells.
| Cells | Drugs | Pathways | |||||
|---|---|---|---|---|---|---|---|
|
| |||||||
| PKA | StAR | PKC | PLC | ERK | AR | ||
| Normal Leydig cells | CS | + | N/A | − | N/A | N/A | N/A |
| Cordycepin | + | + | N/A | N/A | N/A | + | |
| MA-10 cells | CS | + | + | + | + | N/A | N/A |
| Cordycepin | + | − | + | + | + | + | |
+ = stimulation; − = no effect; N/A = not examined yet.
