Table 1.
Characteristics of the 33 trials included in the meta-analysis.
| Groups | NP | No. of nodules | Size (mm) | CPC (A/B/C) | Follow-up | |||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| NO. | First author | Year | Country | Type | MWA | RFA | MWA | RFA | Ages(Y) | Male (%) | MWA | RFA | MWA | RFA | MWA | RFA | MWA | RFA |
| 1 | Abdelaziz | 2014 | Egypt | RCT | MWA | RFA | 66 | 45 | 55 | 71 | 76 | 52 | 29 (9.7) | 29.5 (10.3) | 25/41/0 | 24/21/0 | 40 | 40 |
| 2 | Chinnaratha | 2015 | Australia | Retrospective | MWA | RFA | 25 | 101 | 62 | 78 | 31 | 114 | NR | NR | NR | NR | 14 | 14 |
| 3 | Cillo U | 2014 | Italy | Prospective | MWA | RFA | 28 | 28 | 64 | 80 | NR | NR | 25 (15–53) | 27 (12–60) | NR | NR | 24 | 24 |
| 4 | Correa G | 2014 | USA | Retrospective | MWA | RFA | 67 | 67 | 55 | NR | 127 | 127 | NR | NR | NR | NR | 18 | 31 |
| 5 | Di Vece | 2014 | Italy | RCT | MWA | RFA | 20 | 20 | 61 | 73 | 20 | 20 | 36 (22–69) | 32 (23–64) | NR | NR | NR | NR |
| 6 | Ding J | 2013 | China | Retrospective | MWA | RFA | 113 | 85 | 59 | 77 | 131 | 98 | 25.5 (8.9) | 23.8 (8.1) | 75/38/0 | 49/36/0 | 18 | 28 |
| 7 | Hompes | 2010 | Belgium | Retrospective | MWA | RFA | 6 | 13 | 60 | 47 | 16 | 13 | NR | NR | NR | NR | 6 | NR |
| 8 | Kamal A | 2019 | Egypt | RCT | MWA | RFA | 28 | 28 | 55 | 77 | 34 | 34 | 32.5 (9.2) | 32.8 (9.1) | 22/6/0 | 22/6/0 | 12 | 12 |
| 9 | Kuang | 2011 | China | Retrospective | MWA | RFA | 19 | 31 | 55 | 94 | 19 | 31 | NR | NR | NR | NR | 45 | 45 |
| 10 | Lee KF | 2017 | China | Retrospective | MWA | RFA | 26 | 47 | 60 | 81 | 28 | 52 | 37.5 (20–60) | 31 (20–60) | 23/3/0 | 42/5/0 | 48 | 53 |
| 11 | Liu Y | 2013 | China | Retrospective | MWA | RFA | 35 | 54 | 53 | 61 | 62 | 70 | 23 (10) | 25 (10) | NR | NR | 32 | 32 |
| 12 | Liu W | 2018 | China | Retrospective | MWA | RFA | 126 | 436 | 56 | 90 | 162 | 482 | 22.5 (17–29) | 23 (18–30) | NR | NR | 37 | 34 |
| 13 | Lu M | 2005 | China | Retrospective | MWA | RFA | 49 | 53 | 52 | 85 | 98 | 72 | 25 (12) | 26 (12) | 22/27/0 | 47/6/0 | 25 | 25 |
| 14 | Ohmoto K | 2009 | Japan | Retrospective | MWA | RFA | 49 | 34 | 65 | 80 | 56 | 37 | 17 (8–20) | 16 (7–20) | 31/14/4 | 20/11/3 | 34 | 26 |
| 15 | Potrezzke | 2016 | USA | Retrospective | MWA | RFA | 99 | 55 | 61 | 79 | 136 | 69 | 22 (20–23) | 24 (22–26) | NR | NR | 24 | 31 |
| 16 | Qian | 2012 | China | Prospective | MWA | RFA | 22 | 20 | 54 | 93 | 22 | 20 | 21 (4) | 20 (5) | NR | NR | 5 | 5 |
| 17 | Sakaguchi | 2009 | Japan | Retrospective | MWA | RFA | 142 | 249 | 65 | 71 | 142 | 249 | 22.8 (7.4) | 24.8 (8.9) | 86/56/0 | 147/98/4 | NR | NR |
| 18 | Santambrogio R | 2017 | Italy | Retrospective | MWA | RFA | 60 | 94 | 69 | 73 | NR | NR | 21.5 (5.3) | 19.2 (5) | 60/0/0 | 94/0/0 | 27 | 27 |
| 19 | Sever IH | 2018 | Turkey | Retrospective | MWA | RFA | 20 | 20 | 64 | 70 | 30 | 25 | 28 (10) | 24 (11) | 14/4/2 | 11/4/5 | 6 | 6 |
| 20 | Shady | 2017 | USA | Retrospective | MWA | RFA | 48 | 62 | NR | 66 | 60 | 85 | 17 (7–37) | 18 (6–45) | NR | NR | 29 | 56 |
| 21 | Shibata T | 2002 | Japan | RCT | MWA | RFA | 36 | 36 | 63 | 69 | 46 | 48 | 22 (9–34) | 23 (10–37) | 19/17/0 | 21/15/0 | 18 | 18 |
| 22 | Simo KA | 2011 | USA | Retrospective | MWA | RFA | 13 | 22 | 59 | 74 | 15 | 27 | 23.1 (14–39) | 25.3 (12–44) | 7/6/0 | 12/7/3 | 7 | 19 |
| 23 | Sparchez Z | 2019 | Romania | Retrospective | MWA | RFA | 17 | 44 | 61 | 52 | 20 | 62 | 25.5 (15–33) | 25 (16.5–30) | NR | NR | NR | NR |
| 24 | Tian W | 2014 | China | RCT | MWA | RFA | 60 | 60 | 55 | 78 | 79 | 86 | 26 (13) | 22 (9) | NR | NR | NR | NR |
| 25 | van Tilborg | 2016 | Netherlands | Retrospective | MWA | RFA | 15 | 96 | 61 | 65 | 32 | 139 | 25 (4–65) | 24 (2–68) | NR | NR | 49 | NR |
| 26 | Vietti V | 2018 | Switzerland | RCT | MWA | RFA | 71 | 73 | 66 | 84 | 98 | 104 | 18 (6.5) | 18 (7.1) | 57/14/0 | 53/20/0 | 26 | 25 |
| 27 | Vogl TJ | 2015 | Germany | Retrospective | MWA | RFA | 28 | 25 | 59 | 79 | 36 | 32 | 36 (9–50) | 32 (8–45) | NR | NR | NR | NR |
| 28 | Xu HX | 2004 | China | Retrospective | MWA | RFA | 54 | 43 | 53 | 86 | 112 | 78 | 25 (11) | 26 (14) | NR | NR | NR | NR |
| 29 | Xu Y | 2017 | China | Retrospective | MWA | RFA | 301 | 159 | 54 | 80 | NR | NR | 17 (3) | 17 (3) | 278/23/0 | 140/19/0 | 53 | 62 |
| 30 | Yang B | 2017 | China | Retrospective | MWA | RFA | 71 | 108 | 50 | 65 | 121 | 188 | NR | NR | NR | NR | 39 | 39 |
| 31 | Yin X | 2009 | China | Retrospective | MWA | RFA | 50 | 59 | 53 | 87 | NR | NR | NR | NR | NR | NR | 22 | 22 |
| 32 | Yu J | 2017 | China | RCT | MWA | RFA | 203 | 200 | NR | NR | 265 | 251 | 27 (10) | 26 (10) | NR | NR | 35 | 35 |
| 33 | Zhang L | 2013 | China | Retrospective | MWA | RFA | 77 | 78 | 54 | 85 | 105 | 97 | 22 (4) | 23 (4) | 77/0/0 | 78/0/0 | 25 | 26 |