Table 4.

Univariate log-rank test and multivariate Cox proportional hazards model for survival.

Variables	Univariate log-rank test	Multivariate Cox regression analysis*
	p	HR	95% CI	p
Overall survival
Age ≥ 65 years	0.143	4.308	0.389-47.680	0.234
Male sex	0.972
BMI ≥ 25	0.659
Perforation	0.380
Obstruction	0.400
sT4	0.024**	8.007	0.866-74.023	0.067
Poorly differentiated	0.481
Lymphovascular invasion	0.561
Harvested LN < 12	0.010**	5.054	0.492-51-860	0.173
Adjuvant chemotherapy	0.553
Disease-free survival
Age ≥ 65 years	0.157	0.354	0.045-2.760	0.322
Male sex	0.484
BMI ≥ 25	0.222
Perforation	0.512
Obstruction	0.548
sT4	0.017**	7.303	1.314-40.596	0.023**
Poorly differentiated	0.781
Lymphovascular invasion	0.424
Harvested LN < 12	0.025**	2.938	0.304-28.376	0.352
Adjuvant chemotherapy	0.123	0.199	0.031-1.287	0.090

^*After all variables that showed p ≥ 0.2 in univariate analysis were removed, multivariate Cox regression analysis was performed.

^**Statistical significance, p < 0.05.

HR, hazard ratio; CI, confidence interval; BMI, body mass index; sT4, surgical stage T4; LN, lymph nodes.