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. Author manuscript; available in PMC: 2022 Nov 16.
Published in final edited form as: Nat Methods. 2022 May 16;19(5):567–575. doi: 10.1038/s41592-022-01459-6

Figure 2: PASTE results on simulated ST slices from a breast cancer ST slice from [35].

Figure 2:

(a) Average percentage of spots correctly aligned by PASTE in PAIRWISE SLICE ALIGNMENT mode using α = 0 (gene expression data only), α = 1 (spatial information only), and α = 0.1 (both) as a function of the added pseudocount δ. The dotted line represents the maximum possible accuracy. (b) Average percentage of spots correctly aligned by PASTE in CENTER SLICE INTEGRATION mode between the original center slice and the simulated slices. (c) Difference between the gene expression matrix of the true center slice and the gene expression matrix inferred by PASTE and by Scanorama.