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. 2022 Jul 28;12:12966. doi: 10.1038/s41598-022-17349-y

Table 3.

Statistical comparison between the results obtained by the proposed ISE potentiometric method and the official method for determination of PALO in its pure form.

Parameter ISE potentiometric methoda Official methodb
Ionophore-free sensor Ionophore-doped sensor
Mean 99.69 100.04 100.33
SD 0.65 0.35 0.38
SE 0.21 0.12 0.22
n 9 9 3
Variance 0.42 0.12 0.14
Student’s t-test 2.10 (2.23)c 1.16 (2.23)c NA
F-test 3 (19.37)c 1.17(4.46)c NA

a9 determinations of 3 concentration levels by the proposed ISE method.

b3 determinations of 3 concentrations by USP 41, HPLC–UV method for PALO.

cThe values in parentheses are the corresponding tabulated values of t and F at p = 0.05.