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. 2022 May 26;11(4):1541–1557. doi: 10.1007/s40121-022-00654-4

Table 2.

Biochemical parameter of healthy, uninfected controls and HIV-infected patients

Control Naïve ART-treated p value
Glucose (mg/dl) 87.64 ± 1.77 94.73 ± 2.42 * 93.00 ± 2.20 0.039
Insulin (µU/ml) 9.25 ± 1.54 13.16 ± 1.78 9.90 ± 0.57 0.190
HOMA-IR 2.03 ± 0.33 3.40 ± 0.52 * 2.19 ± 0.16 0.030
Triglycerides (mg/dl) 73.28 ± 5.21 124.47 ± 14.95 ** 117.87 ± 17.73 * 0.004
Cholesterol (mg/d) 184.40 ± 5.66 160.27 ± 8.70 179.87 ± 8.76 0.065
HDL (mg/dl) 62.42 ± 3.83 39.53 ± 2.77 *** 51.47 ± 3.76 0.001
LDL (mg/dl) 110.26 ± 4.26 95.93 ± 7.57 99.00 ± 6.47 0.167
GOT/AST (U/L) 20.88 ± 1.62 21.29 ± 1.74 18.86 ± 1.25 0.607
GPT/ALT (U/L) 18.68 ± 1.60 23.00 ± 2.29 18.43 ± 1.72 0.211

Variables are represented as mean ± standard error mean. P value refers to the comparison between three groups (control vs. naïve vs. ART). Statistically significant p values are in italics. Asterisks indicate statistically significant differences with respect to control group (*p < 0.05, **p < 0.01 and ***p < 0.001)

ART antiretroviral treatment, GOT/AST glutamic oxaloacetic transaminase or aspartate aminotransferase, GPT/ALT pyruvic glutamic transaminase or alanine aminotransferase, HDL high-density lipoprotein, HOMA-IR homeostatic model assessment-insulin resistance, LDL low-density lipoprotein