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. 2022 Jul 15;10:964744. doi: 10.3389/fchem.2022.964744

TABLE 2.

The results of method validation in terms of linearity, sensitivity, precision, and recovery.

Name Linear range (ng·mL−1) Equation R2 LOD (ng·mL−1) LOQ (ng·mL−1) Precision a (mean ± SD) Recovery a (RSD, %)
Cryptotanshinone 0.01–100 y = 1E-05x −1.5897 0.9919 0.009 0.030 48.23 ± 2.58 5.35
Dihydrotanshinone 0.01–100 y = 2E-05x −2.1578 0.9916 0.003 0.010 53.72 ± 3.11 5.79
Tanshinone IIA 0.01–100 y = 2E-05x −1.0208 0.9968 0.017 0.057 49.14 ± 2.12 4.31
Tanshinone I 0.01–100 y = 5E-05x −1.2928 0.9962 0.010 0.033 49.80 ± 1.73 3.47
Salvianate A sodium 0.05–100 y = 0.0003x −8.3986 0.9947 0.135 0.450 52.45 ± 2.08 3.97
Salvianolic acid A 0.05–100 y = 9E-05x + 0.1683 0.9981 0.125 0.417 50.08 ± 1.02 2.04
Rosmarinic acid 0.05–100 y = 0.0002x −8.1191 0.9954 0.090 0.300 47.58 ± 1.99 4.18
a

Spiked level 50 ngmL−1.