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. 2022 Jul 15;10:952679. doi: 10.3389/fchem.2022.952679

TABLE 3.

The anticancer activities of the title compounds 5a5w at 5 μg/ml.

Compound Mortality rate (%)
PC3 K562 Hela A549
5a 0 10.03 ± 1.03 3.82 ± 2.64 15.76 ± 1.30
5b 15.53 ± 1.08 0 2.42 ± 1.06 13.65 ± 2.43
5c 0 19.59 ± 1.30 5.98 ± 1.09 13.74 ± 1.76
5d 5.80 ± 2.13 4.73 ± 2.15 11.37 ± 2.15 13.60 ± 2.80
5e 0 5.30 ± 1.16 0.55 ± 2.24 9.23 ± 1.32
5f 4.08 ± 1.67 21.88 ± 2.24 4.23 ± 1.25 12.47 ± 2.35
5g 0 15.52 ± 1.61 2.75 ± 1.60 14.51 ± 2.35
5h 0 10.98 ± 1.14 0 0.22 ± 1.05
5i 3.98 ± 1.22 3.53 ± 1.95 3.58 ± 1.69 15.15 ± 2.64
5j 31.01 ± 1.90 30.99 ± 2.06 25.22 ± 2.37 22.75 ± 2.94
5k 34.20 ± 2.01 37.80 ± 1.95 34.50 ± 1.89 28.50 ± 2.22
5l 54.94 ± 1.51 15.47 ± 1.38 32.20 ± 2.10 37.35 ± 2.00
5m 0 0 0 0
5n 51.71 ± 1.20 17.11 ± 1.52 30.78 ± 1.45 40.78 ± 1.09
5o 50.52 ± 1.22 19.40 ± 1.64 39.54 ± 2.22 38.78 ± 2.26
5p 9.20 ± 1.45 7.30 ± 2.01 20.40 ± 1.70 16.80 ± 3.26
5q 46.11 ± 1.54 31.40 ± 3.12 37.90 ± 3.01 42.42 ± 1.33
5r 55.32 ± 1.35 15.63 ± 0.96 34.65 ± 1.87 41.36 ± 1.51
5s 22.35 ± 1.16 5.28 ± 1.38 25.14 ± 2.03 15.24 ± 1.67
5t 0.37 ± 1.23 12.46 ± 2.26 6.87 ± 2.07 8.41 ± 2.83
5u 31.01 ± 1.64 30.99 ± 1.34 25.22 ± 2.35 22.75 ± 2.90
5v 64.20 ± 1.12 24.00 ± 1.92 48.25 ± 1.17 34.20 ± 2.31
5w 36.20 ± 1.36 35.40 ± 1.83 32.20 ± 2.62 31.80 ± 2.08
Doxorubicin 94.68 ± 1.05 72.81 ± 1.54 80.43 ± 1.36 89.57 ± 2.07