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Anti-proliferative activity of compounds 1–13 and 15–26 against HepG2 cells.
| Compound | IC50 (μM) | Compound | IC50 (μM) |
|---|---|---|---|
| 1 | >50 | 15 | >50 |
| 2 | >50 | 16 | >50 |
| 3 | >50 | 17 | 25.59 ± 0.41 |
| 4 | >50 | 18 | >50 |
| 5 | >50 | 19 | 2.30 ± 0.30 |
| 6 | >50 | 20 | >50 |
| 7 | >50 | 21 | >50 |
| 8 | >50 | 22 | >50 |
| 9 | >50 | 23 | >50 |
| 10 | >50 | 24 | >50 |
| 11 | >50 | 25 | >50 |
| 12 | >50 | 26 | >50 |
| 13 | >50 | — | — |
Gemcitabine (GEM) was used as a positive control with an IC50 value of 2.32 ± 0.99 μM.
