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The role of TM in tumor treatment. Engineered tumor-targeting bacteria can kill tumors directly (top left), some bacteria can be used as biomarkers for treatments (top right), oral microbial antitumor agents (GEN-001) activates immune cells to synergistically kill tumors and has begun clinical trials (bottom left), TM can produce small molecules and metabolites (e.g. CDDL) to enhance tumor cell resistance to gemcitabine (bottom right).
