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. 2022 Jul 15;13:907481. doi: 10.3389/fimmu.2022.907481

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Copyright © 2022 Soltan, Abdulsahib, Amer, Refaat, Bagalagel, Diri, Albogami, Fayad, Eid, Sharaf, Elhady, Darwish and Eldeen

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Hydrogen bond number-time evolution within the simulated multiepitope vaccine/TLR models. (A) multiepitope vaccine/TLR-4; (B) multiepitope vaccine/TLR-8 models. Left, middle and right panels are respective for the vaccine/TLR protomer A, protomer B, and whole target protein complexes.