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Predicted net charge (electrostatic potential) of the Spike RBD and NTD (folded state) of SARS-CoV-2 VOC, compared with previous main VOC1
| SARS-CoV-2 VOC | Pango Lineage | EP-RBD | EP-NTD |
|---|---|---|---|
| Wuhan | B.1 | 2.15 | 1.30 |
| Alpha | B.1.1.7 | 3.18 | 1.69 |
| Delta | B.1.617.2 | 4.15 | 1.28 |
| Omicron | BA.1.1.529 | 5.22 | -1.10 |
| Omicron | BA.3 | 5.22 | 0.02 |
| Omicron | BA.2 | 5.18 | 0.80 |
| Omicron | BA.2.12.1 | 5.18 | 0.80 |
| Omicron | BA.4 | 5.19 | 1.39 |
| Omicron | BA.5 | 5.19 | 1.39 |
Calculated as described in Ref.4.
