Table 1.

Main clinical and demographic characteristics of subjects.

	HC	sMND	TARDBP	p
Age at MRI	58.99 ± 6.08 [47.63–72.70]	59.07 ± 7.68 [45.00–68.33]	59.78 ± 8.17 [44.14–70.95]	0.952
Sex (M/F)	11/11	6/5	6/5	0.958
Scanner type (S1/S2)	18/4	8/3	8/3	0.785
Education (years)	12.19 ± 3.34 [8–18]	12.73 ± 3.44 [6–17]	10.33 ± 3.39 [5–16]	0.265
Disease duration	–	63.0 ± 90.02 [8.00–277.00]	16.93 ± 17.61 [5.00–67.00]	0.113
ALSFRS-r	–	33.90 ± 6.37 [23–42]	34.18 ± 8.82 [20–44]	0.935
Disease progression rate	–	0.73 ± 0.74 [0.08–2.11]	1.40 ± 1.23 [0.16–4.00]	0.135

Values are numbers or means ± standard deviations [range]. p-values refer to Pearson's chi square or ANOVA models (as appropriate).

ALSFRS-r, revised version of the Amyotrophic Lateral Sclerosis Functional Rating Scale; F, female; HC, healthy controls; M, male; MND, motor neuron disease; S1/S2, Scanner 1/Scanner 2; sMND, sporadic MND. –, not applicable.