Table 1.
UPA 15 mg QD | PBO to UPA 15 mg QD | Total | |
Baseline, mean (SD) | 7.5 (11.1) n=92 | 8.8 (12.1) n=94 | 8.1 (11.6) n=186 |
Change from baseline to week 104 | |||
Mean (95% CI†) | 0.6 (0.1 to 1.1) n=69 | 0.8 (0.2 to 1.4) n=67 | 0.7 (0.3 to 1.1) n=136 |
LS mean (95% CI†) | 0.6 (0.0 to 1.2) n=69 | 0.9 (0.3 to 1.5) n=67 | 0.7 (0.3 to 1.2) n=136 |
*Data were obtained in a dedicated reading session that included baseline and week 104 images.
†95% CIs were calculated based on the t-distribution.
LS, least squares; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; PBO, placebo; QD, once daily; UPA, upadacitinib.