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. 2022 Jul 27;8(2):e002280. doi: 10.1136/rmdopen-2022-002280

Table 1.

Baseline mean and mean change from baseline to week 104 in mSASSS*

UPA 15 mg QD PBO to UPA 15 mg QD Total
Baseline, mean (SD) 7.5 (11.1) n=92 8.8 (12.1) n=94 8.1 (11.6) n=186
Change from baseline to week 104
Mean (95% CI†) 0.6 (0.1 to 1.1) n=69 0.8 (0.2 to 1.4) n=67 0.7 (0.3 to 1.1) n=136
LS mean (95% CI†) 0.6 (0.0 to 1.2) n=69 0.9 (0.3 to 1.5) n=67 0.7 (0.3 to 1.2) n=136

*Data were obtained in a dedicated reading session that included baseline and week 104 images.

†95% CIs were calculated based on the t-distribution.

LS, least squares; mSASSS, modified Stoke Ankylosing Spondylitis Spine Score; PBO, placebo; QD, once daily; UPA, upadacitinib.