Table 5.
Unadjusted incidence of oesophagitis, ulcers and IBD in women who were iron deficient compared with those who were not iron deficient
| Iron deficient | Non-iron deficient | P value | |||||
| Sample size (n) | Pathology* (n) | Incidence/1000 patients (95% CI) |
Sample size (n) | Pathology* (n) | Incidence/1000 patients (95% CI) |
||
| Anaemic women (n=9783) | |||||||
| Oesophagitis | |||||||
| Age 20–49 years | 6627 | 100 | 15.09 (12.42 to 18.32) | 3156 | 66 | 20.91 (16.47 to 26.52) | 0.04 |
| 20–29 | 379 | 6 | 15.83 (7.28 to 34.10) | 269 | 2 | 7.43 (2.04 to 26.70) | 0.48 |
| 30–39 | 1656 | 28 | 16.91 (11.72 to 24.33) | 935 | 24 | 25.67 (17.31 to 37.91) | 0.13 |
| 40–49 | 4592 | 66 | 14.37 (11.31 to 18.24) | 1952 | 40 | 20.49 (15.08 to 27.78) | 0.07 |
| Ulcer | |||||||
| Age 20–49 years | 6627 | 59 | 8.90 (6.91 to 11.47) | 3156 | 41 | 12.99 (9.59 to 17.58) | 0.06 |
| 20–29 | 379 | 1 | 2.64 (0.47 to 14.79) | 269 | 3 | 11.15 (3.80 to 32.27) | 0.31 |
| 30–39 | 1656 | 10 | 6.04 (3.28 to 11.08) | 935 | 6 | 6.42 (2.94 to 13.93) | 0.90 |
| 40–49 | 4592 | 48 | 10.45 (7.89 to 13.83) | 1952 | 32 | 16.39 (11.64 to 23.05) | 0.045 |
| IBD | |||||||
| Age 20–49 years | 6627 | 24 | 3.62 (2.43 to 5.38) | 3156 | 14 | 4.44 (2.64 to 7.43) | 0.54 |
| 20–29 | 379 | 1 | 2.64 (0.47 to 14.79) | 269 | 1 | 3.72 (0.66 to 20.75) | >0.99 |
| 30–39 | 1656 | 5 | 3.02 (1.29 to 7.05) | 935 | 4 | 4.28 (1.66 to 10.95) | 0.73 |
| 40–49 | 4592 | 18 | 3.92 (2.48 to 6.19) | 1952 | 9 | 4.61 (2.43 to 8.74) | 0.69 |
| Non-anaemic women (n=22 657) | |||||||
| Oesophagitis | |||||||
| Age 20–49 years | 6979 | 82 | 11.75 (9.48 to 14.56) | 15 678 | 221 | 14.10 (12.37 to 16.06) | 0.16 |
| 20–29 | 1010 | 6 | 5.94 (2.73 to 12.90) | 2122 | 17 | 8.01 (5.01 to 12.79) | 0.53 |
| 30–39 | 2068 | 22 | 10.64 (7.04 to 16.06) | 5076 | 56 | 11.03 (8.51 to 14.30) | 0.88 |
| 40–49 | 3901 | 54 | 13.84 (10.63 to 18.02) | 8480 | 148 | 17.45 (14.88 to 20.47) | 0.14 |
| Ulcer | |||||||
| Age 20–49 years | 6979 | 58 | 8.31 (6.43 to 10.73) | 15 678 | 97 | 6.19 (5.07 to 7.54) | 0.07 |
| 20–29 | 1010 | 3 | 2.97 (1.01 to 8.70) | 2122 | 8 | 3.77 (1.91 to 7.42) | >0.99 |
| 30–39 | 2068 | 17 | 8.22 (5.14 to 13.13) | 5076 | 26 | 5.12 (3.50 to 7.49) | 0.12 |
| 40–49 | 3901 | 38 | 9.74 (7.11 to 13.34) | 8480 | 63 | 7.43 (5.81 to 9.49) | 0.18 |
| IBD | |||||||
| Age 20–49 years | 6979 | 30 | 4.30 (3.01 to 6.13) | 15 678 | 65 | 4.15 (3.25 to 5.28) | 0.87 |
| 20–29 | 1010 | 0 | – | 2122 | 7 | 3.30 (1.60 to 6.79) | 0.10 |
| 30–39 | 2068 | 6 | 2.90 (1.33 to 6.32) | 5076 | 15 | 2.96 (1.79 to 4.87) | 0.97 |
| 40–49 | 3901 | 24 | 6.15 (4.14 to 9.14) | 8480 | 43 | 4.95 (3.67 to 6.69) | 0.45 |
Comparisons were made using Fisher’s exact tests.
–, not applicable.
*Within 5 years of the iron deficiency test date.
IBD, inflammatory bowel disease.