TABLE 4.
Clinical characteristics of patients in favorable outcome and poor outcome.
| Variables | Favorable outcome (n = 298) | Poor outcome (n = 452) | P |
| Age, years (IQR) | 61 (52–68) | 62 (54–69) | 0.070 |
| Male, n (%) | 225 (75.5) | 318 (70.4) | 0.123 |
| Cigarette smoking, n (%) | 166 (55.7) | 222 (49.1) | 0.077 |
| Alcohol consumption, n (%) | 129 (43.3) | 185 (58.9) | 0.522 |
| Hypertension, n (%) | 143 (48) | 241 (53.3) | 0.153 |
| Diabetes mellitus, n (%) | 52 (17.4) | 87 (19.2) | 0.535 |
| Coronary heart disease, n (%) | 57 (19.1) | 89 (19.7) | 0.849 |
| Atrial fibrillation, n (%) | 30 (10.1) | 44 (9.7) | 0.881 |
| Previous stroke, n (%) | 36 (12.1) | 67 (14.8) | 0.286 |
| Dyslipidemia, n (%) | 129 (43.3) | 184 (40.7) | 0.483 |
| Antihypertensive therapy, n (%) | 102 (34.2) | 198 (43.8) | 0.009 |
| Hypoglycemic therapy, n (%) | 42 (14.1) | 79 (17.5) | 0.218 |
| Antiplatelet therapy, n (%) | 37 (12.4) | 61 (13.5) | 0.668 |
| Baseline SBP, mmHg (IQR) | 152 (137–163.3) | 155 (140.3–168.8) | 0.016 |
| Baseline DBP, mmHg (IQR) | 89 (80–97) | 90 (82–98) | 0.249 |
| Baseline blood glucose, mmol/L (IQR) | 7.4 (6.4–8.8) | 7.7 (6.7–9.4) | 0.003 |
| Baseline NIHSS score (IQR) | 6 (4–10) | 10 (6–13) | <0.001 |
| ONT, min (IQR) | 180.5 (137.5–230) | 184.5 (146.3–228.8) | 0.662 |
| TOAST | <0.001 | ||
| Large-artery atherosclerosis, n (%) | 75 (25.2) | 199 (44.0) | |
| Small-vessel occlusion, n (%) | 144 (48.3) | 136 (30.1) | |
| Cardioembolism, n (%) | 33 (11.1) | 51 (11.3) | |
| Other determined etiology, n (%) | 9 (3) | 3 (0.7) | |
| Undetermined etiology, n (%) | 37 (12.4) | 63 (13.9) | |
| ALP, U/L (IQR) | 71.4 (60.1–87.2) | 76.6 (63.5–94.3) | 0.002 |
| Globulin, g/L (IQR) | 26.6 (23.9–29.3) | 27.4 (24.7–30.4) | 0.002 |
IQR, inter quartile range; SBP, systolic blood pressure; DBP, diastolic blood pressure; NIHSS, National Institutes of Health Stroke Scale; ONT, onset to needle time; TOAST, Trial of Org 10172 in acute stroke treatment; ALP, alkaline phosphatase.