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. 2022 Jul 15;13:899271. doi: 10.3389/fendo.2022.899271

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Copyright © 2022 Chu, Chan, Yip, Chu, Wang and Pang

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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Heatmaps of metabolites showed patterns of differential metabolite profiles between different treatment groups in plasma. (A) Between controls and EIU as induced by LPS in the plasma; (B) Between EIU induced by LPS and after GTE treatment in the plasma Principal component analysis (PCA) showed (C) comparison of controls and EIU induced by LPS, (D) comparison of EIU induced by LPS and after GTE treatment samples in plasma. Metabolites and their associated biological activities were shown in (E) the plasma of the EIU rats induced by LPS, and (F) the plasma of the EIU rats after GTE treatment.