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. 2022 Jul 15;13:899271. doi: 10.3389/fendo.2022.899271

Figure 5.

Figure 5

The proposed mechanism of how catechins in GTE inhibit phospholipase A2 (PLA2) activity and alleviate retinal inflammation and metabolic stress. (A) The chart shows the relative PLA2 activities in six rat plasma samples of different treatment groups. (B) LPS induced fever caused by LPS induced PLA2 activity to increase lipid digestion and subsequently reduce phosphocholine lipids. Catechins inhibited PLA2 activity, increased PC levels, and subsequently inhibited inflammation. *:- a significant difference between groups; error bar:- standard derivation; horizontal bar:- one-way ANOVA comparison between three groups.