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. 2022 Jul 15;13:862732. doi: 10.3389/fphys.2022.862732

TABLE 7.

The diagnostic efficiency analysis of four AAD biomarkers.

AUC p-value 95% CI Sensitivity (%) Specificity (%) Cutoff (ng/dl) Youden index
LUMICAN 0.636 0.004 0.547–0.725 70.1 57.5 1.865 0.276
PI16 0.739 0.000 0.661–0.816 55.8 78.1 1.973 0.339
FGL1 0.607 0.024 0.512–0.702 90.9 43.8 0.223 0.347
MMP9 0.641 0.003 0.552–0.731 84.4 43.8 0.99 0.282
PI16 + LUM 0.742 0.000 0.665–0.819 90.9 43.8 0.33 0.347
PI16 + FGL1 0.769 0.000 0.693–0.845 71.4 71.2 0.515 0.426
LUMICAN + FGL1 0.653 0.001 0.565–0.741 59.7 71.2 0.517 0.309
LUMICAN + FGL1 + PI16 0.780 0.000 0.707–0.852 67.5 76.7 0.675 0.442