TABLE 1.
Baseline characteristics of AIS patients with mRS of ≤2 and that of >2 at 3 months.
| All (108) | Favourable prognosis (n = 69) | Unfavourable prognosis (n = 39) | p value | |
|---|---|---|---|---|
| Demographic characteristics[n(%) OR median (IQR) OR ‾x ± s] | ||||
| Male, n (%) | 85 (78.70) | 56 (81.16) | 29 (74.36) | 0.466 |
| Age, y, (x ± s) | 64.30 ± 12.61 | 61.23 ± 10.92 | 69.72 ± 13.68 | 0.001 |
| Body mass index, kg/m2 | 24.84 (23.85, 26.74) | 25 (23.75, 26.73) | 24.59 (23.85, 26.80) | 0.595 |
| Medical history [n (%)] | ||||
| Hypertension | 78 (72.22) | 50 (72.46) | 28 (71.79) | 0.556 |
| Diabetes mellitus | 37 (34.26) | 23 (33.33) | 14 (35.90) | 0.835 |
| Hypercholesterolemia | 50 (46.30) | 34 (49.28) | 16 (41.03) | 0.266 |
| Coronary artery disease | 21 (19.44) | 13 (18.84) | 8 (20.51) | 0.511 |
| Atrial fibrillation | 9 (8.33) | 3 (4.35) | 6 (15.38) | 0.046 |
| Smoking habit | 46 (42.59) | 33 (47.83) | 13 (33.33) | 0.103 |
| Stroke characteristics and treatment [n(%) OR median (IQR)] | ||||
| Onset-to-treatment time, h | 2.20 (1.20, 3.38) | 2.5 (1.20, 3.40) | 2 (1.20, 3.30) | 0.699 |
| Mechanical thrombectomy | 21 (19.44) | 6 (8.70) | 15 (38.46) | <0.001 |
| Stroke classification[n (%)] | ||||
| LAA | 65 (60.19) | 36 (52.17) | 29 (74.36) | 0.024 |
| SAO | 36 (33.33) | 28 (40.58) | 8 (20.51) | 0.034 |
| Others | 7 (6.48) | 5 (7.25) | 2 (5.13) | 0.668 |
| Complication | ||||
| sICH | 2 (1.9) | 1 (1.4) | 2 (5.1) | 0.295 |
| General evaluation of admission[n(%) OR median (IQR) OR ‾x ± s] | ||||
| Systolic blood pressure, mm Hg | 150 (140, 168) | 150 (139.50, 168.00) | 150 (140.00, 168.00) | 0.734 |
| Diastolic blood pressure, mm Hg | 82.50 (74.25, 92.75) | 82 (73.50, 93.00) | 86 (75.00, 92.00) | 0.885 |
| Blood glucose concentration, g/L | 7.90 (6.52, 10.30) | 7.40 (6.20, 9.70) | 8.90 (7.60, 11.10) | 0.026 |
| Glycated hemoglobin | 6.15 (5.60, 7.30) | 6 (5.60, 7.20) | 6.20 (5.70, 7.30) | 0.512 |
| CRP, mg/L | 2.13 (1.12, 5.89) | 1.89(0.80, 4.17) | 5.89 (1.75, 12.31) | <0.001 |
| Homocysteine, μmol/L | 14.80 (11.60, 17.40) | 14.5 (11.40, 18.35) | 14.9 (12.20, 16.10) | 0.883 |
| TC, mmol/L | 1.71 (1.03, 2.70) | 1.76 (1.10, 2.74) | 1.7 (0.99, 2.63) | 0.468 |
| Cholesterol, mmol/L | 4.62 ± 1.06 | 4.62 ± 1.11 | 4.6 ± 1.0 | 0.922 |
| HDL, mmol/L | 1.12 (0.94, 1.30) | 1.12 (0.96, 1.36) | 1.06 (0.89, 1.27) | 0.359 |
| LDL, mmol/L | 2.65 ± 0.92 | 2.64 ± 0.97 | 2.7 ± 0.82 | 0.786 |
| NIHSS score | 5 (3, 12) | 5 (3, 6.50) | 12.00 (6, 18) | <0.001 |
| WBC, ×109/L | 7.38 (6.14, 9.14) | 7.20 (576, 8.79) | 7.87 (6.52, 10.61) | 0.120 |
| Neutrophils, ×109/L | 4.71 (3.71, 6.54) | 4.47 (3.53, 5.67) | 5.37 (4.06, 7.95) | 0.025 |
| Lymphocytes, ×109/L | 1.83 (1.32, 2.26) | 1.90 (1.52, 2.33) | 1.48 (1.16, 2.19) | 0.053 |
| Neutrophil-to-lymphocyte ratio | 2.61 (1.84, 4.47) | 2.35 (1.66, 3.46) | 3.35 (2.42, 5.55) | 0.010 |
| Platelet count, ×1,000/mm3 | 208.5 (175, 242) | 220 (177.50, 245) | 201 (167, 232) | 0.065 |
| Syndecan-1,ng/mL | 131.19 ± 54.35 | 115.60 ± 47.71 | 158.77 ± 54.97 | <0.001 |
NIHSS, NIH stroke scale; IQR, interquartile range; CRP, C-reactive protein; HDL, high-density lipoprotein; LDL, low-density lipoprotein; TC, triglyceride; sICH, symptomatic intracranial hemorrhage.