. 2022 May 20;122(14):12308–12369. doi: 10.1021/acs.chemrev.1c00862

Table 4. Rhodium Catalyzed Hydroformylation Using a 4 × 4 Library of 6-DPPAP (160a–d) and 3-DPPICon (161a–d) Derivatives (for Structures See Scheme 34)^a with the Activity in TOF^b and Selectivity in l:b Ratio Provided^c.

	3-DPPIcon monomer
6-DPPAP monomer	161a (R = Ph)	161b (R = (4-MeOPh)	161c (R = 3,5-bis-CF₃Ph)	161d (R = 4-FPh)
160a (R = Ph)	2425	1040	2732	2559
160a (R = Ph)	94:6	94:6	96:4	95:5
160b (R = 4-MeOPh)	2033	1058	1281	1772
160b (R = 4-MeOPh)	93:7	92:8	96:4	94:6
160c (R = m-tolyl)	3537	1842	1808	2287
160c (R = m-tolyl)	94:6	93:7	96:4	94:6
160d (R = 3,5-bis-CF₃Ph)	7439	2695	7465	8643
160d (R = 3,5-bis-CF₃Ph)	94:6	95:5	94:6	94:6

Reaction conditions: [Rh(CO)₂(acac)], [Rh]:(160):(161):1-octene = 1:10:10:7500, 10 bar H₂/CO (1:1), toluene (c_0(1-octene) = 2.91 M), 5 h. Catalyst preformation: 5 bar CO/H₂ (1:1), 30 min, RT to 80 °C.

Turnover frequency (TOF) in mol_substrate/mol_catalyst·h^–1.

Regioselectivity in linear (l) to branched (b) (l:b) ratio.

Table 4. Rhodium Catalyzed Hydroformylation Using a 4 × 4 Library of 6-DPPAP (160a–d) and 3-DPPICon (161a–d) Derivatives (for Structures See Scheme 34)a with the Activity in TOFb and Selectivity in l:b Ratio Providedc.

Table 4. Rhodium Catalyzed Hydroformylation Using a 4 × 4 Library of 6-DPPAP (160a–d) and 3-DPPICon (161a–d) Derivatives (for Structures See Scheme 34)^a with the Activity in TOF^b and Selectivity in l:b Ratio Provided^c.