Table 1.

Excipient Molar Ratios of the LNP Formulations in Libraries A and B

Library A
LNP Name	C14–4	DOPE	Chol	PEG
A1	15	10	20	0.5
A2	15	20	25	1
A3	15	30	30	2.5
A4	15	40	35	5
A5	25	10	25	2.5
A6	25	20	20	5
A7	25	30	35	0.5
A8	25	40	30	1
A9	35	10	30	5
A10	35	20	35	2.5
A11	35	30	20	1
A12	35	40	25	0.5
A13	45	10	35	1
A14	45	20	30	0.5
A15	45	30	25	5
A16	45	40	20	2.5
S2	35	16	46.5	2.5
Library B
name	C14–4	DOPE	Chol	PEG
B1	35	30	20	2.5
B2	35	35	20	2.5
B3	35	40	20	2.5
B4	35	30	25	2.5
B5	35	35	25	2.5
B6	35	40	25	2.5
B7	40	30	20	2.5
B8	40	35	20	2.5
B9	40	40	20	2.5
B10	40	30	25	2.5
B11	40	35	25	2.5
B12	40	40	25	2.5