Table 5:
Selection percentage and the average number of patients treated at each dose for the two subgroups under the BIPSE design with an alternative data-generating process.
Z=0 |
Z=1 |
|||||||||
---|---|---|---|---|---|---|---|---|---|---|
Scenario 1 | ||||||||||
Sel % | 0.036 | 0.680 | 0.172 | 0.002 | 0.004 | 0.362 | 0.627 | 0.006 | 0.000 | 0.000 |
# of patients | 7.5 | 7.4 | 6.4 | 3.7 | 1.8 | 10.0 | 9.0 | 5.3 | 1.9 | 0.5 |
Scenario 2 | ||||||||||
Sel % | 0.000 | 0.108 | 0.692 | 0.138 | 0.032 | 0.000 | 0.132 | 0.716 | 0.126 | 0.022 |
# of patients | 4.5 | 7.3 | 7.5 | 6.0 | 3.7 | 6.1 | 7.8 | 7.2 | 5.5 | 3.2 |
Scenario 3 | ||||||||||
Sel % | 0.002 | 0.002 | 0.004 | 0.012 | 0.978 | 0.000 | 0.000 | 0.000 | 0.018 | 0.980 |
# of patients | 3.5 | 6.4 | 6.8 | 6.8 | 6.2 | 4.9 | 6.0 | 6.6 | 6.6 | 5.8 |
Scenario 4 | ||||||||||
Sel % | 0.000 | 0.066 | 0.584 | 0.282 | 0.066 | 0.028 | 0.668 | 0.292 | 0.010 | 0.000 |
# of patients | 6.0 | 6.8 | 6.8 | 5.8 | 4.2 | 6.7 | 7.1 | 6.8 | 5.7 | 4.1 |
Scenario 5 | ||||||||||
Sel % | 0.000 | 0.002 | 0.038 | 0.248 | 0.712 | 0.002 | 0.038 | 0.600 | 0.204 | 0.156 |
# of patients | 4.8 | 6.3 | 7.0 | 6.7 | 5.1 | 5.8 | 7.4 | 7.1 | 5.7 | 4.1 |
Scenario 6 | ||||||||||
Sel % | 0.066 | 0.458 | 0.314 | 0.078 | 0.068 | 0.132 | 0.648 | 0.196 | 0.020 | 0.000 |
# of patients | 7.0 | 8.0 | 7.1 | 4.6 | 2.7 | 10.6 | 11.2 | 5.4 | 2.1 | 0.6 |
Scenario 7 | ||||||||||
Sel % | 0.000 | 0.006 | 0.514 | 0.386 | 0.094 | 0.000 | 0.122 | 0.726 | 0.124 | 0.028 |
# of patients | 5.5 | 6.8 | 6.9 | 6.1 | 4.4 | 6.0 | 6.9 | 6.9 | 6.1 | 4.3 |
Scenario 8 | ||||||||||
Sel % | 0.000 | 0.002 | 0.014 | 0.238 | 0.744 | 0.000 | 0.000 | 0.048 | 0.304 | 0.646 |
# of patients | 4.8 | 6.2 | 6.8 | 6.7 | 5.5 | 4.9 | 6.4 | 7.0 | 6.4 | 5.1 |
Scenario 9 | ||||||||||
Sel % | 0.000 | 0.000 | 0.196 | 0.380 | 0.422 | 0.008 | 0.456 | 0.412 | 0.032 | 0.090 |
# of patients | 5.2 | 6.9 | 6.9 | 6.2 | 4.8 | 6.6 | 7.4 | 6.8 | 5.2 | 3.9 |
Scenario 10 | ||||||||||
Sel % | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 | 0.000 |
# of patients | 1.7 | 0.8 | 0.1 | 0.0 | 0.0 | 2.1 | 1.5 | 0.3 | 0.0 | 0.0 |