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. 2022 Jul 29;23:58. doi: 10.1186/s40360-022-00596-0

Table 3.

Zone of inhibition and minimum inhibitory concentration (MIC) of 2E,2′E) dibutylstannanediyl bis(4-((4-nitrophenyl)amino)-4-oxobut-2-enoate (DTN) against three strains of H.pylori, using disk diffusion method

Samples Zone of Inhibition (mm) MIC (μg/mL)
0.5 μg/disk 1 μg/disk 2 μg/disk 4 μg/disk 8 μg/disk 16 μg/disk 32 μg/disk
STRAIN I: j63 (cagA-)
DTN 2.33 ± 0.66 3.66 ± 0.33 4.66 ± 0.33 6.0 ± 0.57 10 ± 1.15 12.66 ± 0.33 15.33 ± 1 12
Metronidazole 3.66 ± 0.33 4.66 ± 0.33 5.33 ± 0.66 7 ± 0.57 10.33 ± 1.20 14.66 ± 0.88 22 ± 1.15 4
STRAIN II: j196 (cagA-)
DTN 3 ± 0.57 3.66 ± 0.66 5 ± 0.57 6 ± 1.73 9.33 ± 0.66 12.66 ± 0.88 19 ± 0.57 10
Metronidazole 4 ± 0.57 5 ± 0.57 5 ± 0.57 7.33 ± 0.88 10.33 ± 1.20 15 ± 1.73 20.66 ± 2.30 6
STRAIN III: j107 (cagA+)
DTN 2.66 ± 0.33 4 ± 0.57 4 ± 0.57 6.33 ± 0.66 10.33 ± 1.20 14 ± 0.57 18.66 ± 0.88 10
Metronidazole 4 ± 0.57 4.66 ± 0.33 5.66 ± 0.88 8 ± 1.15 11.33 ± 0.66 15.66 ± 0.33 22.66 ± 0.66 4