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. 2022 Jul 29;23:58. doi: 10.1186/s40360-022-00596-0

Table 4.

Protective effect of 2E,2′E) dibutylstannanediyl bis(4-(4-nitrophenyl)amino)-4-oxobut-2-enoate (DTN) and omeprazole against ethanol-induced gastric ulcer rats tissues

Treatment (mg/Kg) Ulcer index ± SEM % Inhibition
Saline (10 mL/Kg) 0 ± 0 _
Ethanol (1 mL/100 g) 10 ± 0.25### 0
DTN (5 mg/Kg) + Ethanol (1 mL/100 g) 5.9 ± 0.29*** 41
DTN (10 mg/Kg) + Ethanol (1 mL/100 g) 4.2 ± 0.37*** 58
DTN (30 mg/Kg) + Ethanol (1 mL/100 g) 1 ± 0.27*** 90
Omeprazole (20 mg/Kg) + Ethanol (1 mL/100 g) 1 ± 0.22*** 90

Data expressed as mean ± SEM (n = 5). One way ANOVA with post-hoc Tukey’s test

###P < 0.001 vs. saline group, ***P < 0.001 vs. ethanol group