Table 2.

Odds ratio of valve surgery during admission and hazard ratio of 30 day postoperative mortality for patients with infective endocarditis in the study period 1999–2018

	Valve surgery during admission		30 day postoperative mortality
Calendar periods	Odds ratio (95% CI) Adjusted1	P-value	Hazard ratio (95% CI) Adjusted2	P-value
1999–2003	1.00 (ref.)	–	1.00 (ref.)	–
2004–2008	1.14 (0.96–1.35)	0.133	0.96 (0.65–1.41)	0.840
2009–2013	1.20 (1.02–1.42)	0.030	0.43 (0.28–0.67)	< 0.001
2014–2018	1.10 (0.93–1.29)	0.266	0.55 (0.37–0.83)	0.004

This table shows the associated odds ratios of valve surgery and 30 day postoperative mortality when adjusting for covariates for patients with first-time infective endocarditis between 1999 and 2018

Odds Ratio > 1 = increased likelihood. Hazard ratio > 1 = increased rate. Reference (ref.)

¹Model adjusted for: calendar period, age groups, sex, prior prosthetic heart valve, diabetes, renal disease, liver disease, atrial fibrillation/flutter, congestive heart failure, myocardial infarction, disease of the mitral valve, disease of the aortic valve, ischemic/haemorrhagic stroke, chronic obstructive lung disease, malignancy. ²Model adjusted for: calendar period, age (continues), sex, prior prosthetic heart valve, diabetes, renal disease, liver disease, atrial fibrillation/flutter, congestive heart failure, myocardial infarction, disease of the mitral valve, disease of the aortic valve, ischemic/haemorrhagic stroke, chronic obstructive lung disease, malignancy