Table 1.
Overview of data collected within NAPKON by cohort platform
| Category | Features | Collected in | ||
|---|---|---|---|---|
| SUEP | HAP | POP | ||
| Socio-demographic data | Age, sex, residence, marital status | x | x | x |
| Educational level and employment status (e.g. general education degree, vocational degree) | x | x | x | |
| Clinical data: pre-infection anamnestic data | Pre-infection lifestyle (e.g. sports activity, dietary pattern) | x | x | |
| Pre-infection smoking and alcohol consumption | x | x | x | |
| Pre-infection health status and functionality (e.g. Barthel Index, care level, Clinical Frailty Scale) | x | x | x | |
| Pre-infection medication | x | x | ||
| Vaccination status | x | x | x | |
| Comorbidities | x | x | x | |
| Directives for medical decisions (e.g. power of attorney, patient decree) | x | x | ||
| Clinical data: parameters in the observational period | Infrastructural treatment context (e.g. health care facility, involved disciplines) | x | x | x |
| Smoking and alcohol consumption | x | x | ||
| Health status and functionality (e.g. Barthel index, care level, Clinical Frailty Scale) | x | x | x | |
| Symptoms, events | x | x | x | |
| Clinically indicated diagnostics (vital signs, pulmonary diagnostics, laboratory parameters, microbiology & virology, radiological findings, functional diagnostics) | x | x | x | |
| Intensive care scores (e. g. SOFA, SAPS) | x | x | ||
| Therapeutic measures (medication, interventions, surgery, complementary medicine) | x | x | x | |
| Pediatric-specific variable extensions (e.g. perinatal medical history, congenital defects, effects on development) | x | |||
| Imaging data | Clinically indicated diagnostic imaging data | x | x | |
| Study-related MRI scans | x | x | ||
| Study related CT-Thorax scans | x | |||
| Study-related echocardiographies | x | x | x | |
| Patient-reported outcome measures (PROM) | Cognitive function (e.g. PROMIS Kognition) | x | x | x |
| Dypsnea (e.g. Modified Medical Research Council Dyspnea Scale, PROMIS Dyspnoe) | x | x | x | |
| Fatigue (e.g. Chalder Fatigue Scale, FACIT-F) | x | x | x | |
| Functional physical status (e.g. Activities of Daily Living) | x | x | x | |
| Mental health (e.g. GAD-7, Brief Resilience Scale) | x | x | x | |
| Pain (e.g. DN2, HIT-6) | x | x | x | |
| Quality of life (e.g. EQ-5D-5L) | x | x | x | |
| Metadata | Study-related metadata (e.g. data quality assessment, protocol deviation) | x | x | x |
| Digital Imaging and Communications in Medicine (DICOM) header information | x | x | x | |
| Biosample accompanying metadata (e.g. regarding transport, processing and storage) | x | x | x | |