Fig. 5 |. XPLoR-NIH AmB sponge structure.

a, Lowest distance restraint energy (6.8 kcal) XPLOR-NIH structure of the AmB sponge (3 × 3 × 3) lattice which consists of asymmetric head-to-tail homodimers. b, Minimal head-to-tail asymmetric unit of the AmB sponge. State A is shown in orange and state B in blue. In state B, the gauche C5–C6–C7–C8 dihedral is outlined in blue. c, Representative head-to-tail interactions between AmB molecules in the lattice derived from ¹³C–¹³C SSNMR experiments (Fig. 4a–c and Supplementary Fig. 4). d, Representative interactions between ¹⁴N and ¹³C derived from PM-RESPDOR experiments (Fig. 4d). e, Representative staggered interactions between AmB molecules in the lattice derived from ¹³C–¹³C SSNMR experiments (Fig. 4c). f, Representative void volume in the AmB lattice.