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. 2022 Jul 26;29(1):2403–2413. doi: 10.1080/10717544.2022.2067600

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© 2022 The Author(s). Published by Informa UK Limited, trading as Taylor & Francis Group.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/4.0/), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.

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Figure 1. — The characterization of developed actinonin nanoparticles. (a) Representative size distribution of actinonin nanoparticles. The three independent formulations are represented in three different colors. (b)Scanning electron microscopic images of actinonin nanoparticles at 70k X magnification. (c) Transmission electron microscopic image of folate conjugated actinonin nanoparticles. The FTIR data of (d) empty HSA nanoparticles, (e) free actinonin, (f) actinonin nanoparticles. The x-ray diffraction analysis of free drugs and nanoformulated drugs. (g) ENP-empty nanoparticles without folate, (h) FA-folic acid-NHS conjugate, (i) F ACT- free actinonin, (j) ANP- actinonin nanoparticles, The y-axis shows the arbitrary intensity units and x-axis – 2θ˚ (angle in degrees). The experiments were performed in triplicate.