Table 2.

The serum pharmacokinetic parameters after single dose administration of free and nanoformulated actinonin.

Parameters	Actinonin free i.p	Actinonin nano i.p
T½ (h)	0.683 ± 0.06	87.13 ± 0.04
Mean retention time(h)	0.72 ± 0.07	133.82 ± 0.41
K el	7.5519 ± 0.01	0.008 ± 0.001
Cmax (µg/ml)	10.95 ± 0.013	0.41 ± 0.01
AUMC (µgh2/ml)	5.413 ± 0.6	11576.15 ± 0.3
Clearance (mg/l)	463.45 ± 0.2	54.73 ± 0.13

Values are mean ± SD of 3 animals.