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. 2022 Jul 15;13:892701. doi: 10.3389/fimmu.2022.892701

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Copyright © 2022 Sampath, Natarajan, Moideen, Kathamuthu, Hissar, Dhanapal, Jayabal, Ramesh, Tripathy, Ranganathan, Babu and Bethunaickan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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UMAP analysis of monocyte subsets. CD16⁺HLADR⁺ (7,000 cells) were down sampled from monocytes and performed (A) unsupervised (UMAP (UMAP_1_TC1P vs UMAP_2_TC1P) clusters (ungated) and expression of individual monocytes (CD86, HLADR, CD14, CD16, CD64) markers between the study (DR-TB, DS-TB, LTB, HC) population. (B–E) represents the DR-TB, DS-TB, LTB, HC group expression of monocyte marker (islands) subsets using contour plots. (F) shows merged contour plot expression of monocyte subsets among the study individuals.