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. 2022 Jul 15;13:892701. doi: 10.3389/fimmu.2022.892701

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Copyright © 2022 Sampath, Natarajan, Moideen, Kathamuthu, Hissar, Dhanapal, Jayabal, Ramesh, Tripathy, Ranganathan, Babu and Bethunaickan

This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.

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UMAP analysis of DC subsets. HLADR⁺ (10,000 cells) were down sampled for monocytes/granulocytes and performed (A) unsupervised (UMAP (UMAP_1_4ZFH vs UMAP_2_4ZFH) clusters (ungated) and expression of individual DC (CD123, HLADR, CD141, CD11c) markers between the study (DR-TB, DS-TB, LTB, HC) population. (B–E) shows the DR-TB, DS-TB, LTB and HC group expression of DC marker (islands) subsets using contour plots. (F) shows merged contour plot expression of DC subsets among the study individuals.