Table 2.
Clinical findings of fresh-frozen brain tissue from additional FCD patients and controls used in molecular characterization
| ID | Sex | Age | Site of surgery | Subject; cause of death: surgery |
|---|---|---|---|---|
| P1 | Male | 40 | TPO/R | Patient; FCD type IIb |
| P2 | Male | 26 | T/L | Patient; FCD type IIa |
| P3 | Male | 6 | TO/R | Patient; FCD type IIb |
| P13 | Male | 29 | Fr/R | Patient; FCD type IIa |
| P16 | Male | 18 | Fr/L | Patient; FCD type IIb |
| P20 | Male | 32 | Fr/L | Patient; FCD type IIb |
| P21 | Female | 21 | Fr/L | Patient; FCD type IIb |
| C2 | Female | 33 | Fr/R | Control; autopsy: respiratory failure, diffuse lymphoma |
| C20 | Male | 55 | Fr/L | Control; autopsy: septic shock |
| C21 | Female | 37 | Fr/R | Control; autopsy: septic shock/bronchopneumonia |
| C24 | Male | 62 | Fr/R | Control; autopsy: hepatic impairment |
| C23 | Male | 48 | Fr/R | Control; autopsy: pulmonary embolism |
| C25 | Male | 47 | Fr/R | Control; autopsy: septic shock |
| C26 | Male | 50 | T | Control; biopsy: anterior temporal lobectomy |
| C27 | Male | 38 | T | Control; biopsy: anterior temporal lobectomy |
| C28 | Female | 44 | T | Control; biopsy: anterior temporal lobectomy |
| C29 | Male | 40 | T | Control; biopsy: anterior temporal lobectomy |
| C30 | Female | 49 | T | Control; biopsy: anterior temporal lobectomy |
| C31 | Female | 45 | T | Control; biopsy: anterior temporal lobectomy |
| C32 | Male | 51 | T | Control; biopsy: anterior temporal lobectomy |
| C33 | Female | 28 | T | Control; biopsy: anterior temporal lobectomy |
| C34 | Female | 54 | T | Control; biopsy: anterior temporal lobectomy |
Control samples were obtained from autopsies of individuals whose cause of death was non-neurological, and from the biopsy of normal temporal cortex obtained during anterior temporal lobectomy performed in patients with mesial temporal sclerosis. All control samples used in this work were evaluated and considered normal cytoarchitecture of the cerebral cortex by histopathological examination. Fr = frontal; L = left; O = occipital; P = parietal; R = right; T = temporal.