Figure 1.

Lithium mechanism of action and Lithium-induced movement disorders. 5-HT: 5-hydroxytryptamine (serotonin), BDNF: Brain-derived neurotrophic factor, DA: Dopamine, DAG: Diacylglycerol, G: G protein, GSK-3: Glycogen synthase kinase 3, ImPase: Inositol monophosphatase, IP: Inositol phosphate, IPPase: Inositol polyphosphate phosphatase, GABA: Gamma-aminobutyric acid, Glu: Glutamate, MARCKS: Myristoylated alanine-rich C kinase substrate, NE: Norepinephrine, NT: Neurotransmitter, PI: Phosphatidylinositol, PKC: Protein kinase C, PLC: Phospholipase C, SMIT: Sodium-myo-inositol co-transporter, SN: substantia nigra