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. 2016 Apr 25;24(3):539–547. doi: 10.1016/j.jfda.2016.02.007

Table 4.

Antibacterial activities of water, acetone, diethyl ether, and ethanol extracts of Agrimonia eupatoria.

Species Water extract Diethyl ether extract Acetone extract Ethanol extract Tetracycline Ampicillin






MIC MMCa MIC MMC MIC MMC MIC MMC MIC MMC MIC MMC
Escherichia coli ATCC 25922 2.5 3.75 2.5 10 1.25 2.5 1.25 2.5 4 6 0.37 0.5
E. coli >20 >20 >20 >20 10 10 20 >20 2 6 2.1 1.2
Salmonella enterica >20 >20 >20 >20 10 10 20 20 2 2 1 1
Salmonella typhimurium >20 >20 >20 >20 7.5 10 10 20 2 2 2 2
Pseudomonas aeruginosa ATCC 27853 10 20 >20 5 2.5 2.5 5 >20 4 32 128 >128
P. aeruginosa 10 20 20 3.75 0.62 1.25 1.25 >20 >128 >128 128 >128
Proteus mirabilis 5 20 >20 5 2.5 2.5 2.5 20 >128 >128 128 >128
Klebsiella pneumoniae >20 >20 >20 10 10 10 20 >20 4 32 128 >128
Staphylococcus aureus
ATCC 25923
2.5 5 5 5 1.25 2.5 1.25 2.5 1.5 3 0.25 0.75
S. aureus 0.62 2.5 0.31 1.25 0.12 0.62 0.62 1.25 <0.06 <0.06 <0.06 <0.06
Bacillus subtilis
ATCC 6633
1.25 5 0.62 1.87 0.31 0.31 0.62 1.25 0.25 0.37 3 4
B. subtilis 1.25 5 0.62 1.25 0.31 0.62 0.62 1.25 <0.06 0.25 16 128
Bacillus cereus 1.25 1.25 0.62 0.62 0.31 0.31 0.62 0.62 0.25 0.5 4 6
Enterococcus faecalis ATCC 29212 5 >20 5 20 2.5 5 1.87 5 8 12 1 2
E. faecalis >20 >0 >20 >20 10 10 20 20 1 6 4 6
Lactobacillus rhamnosus 1.25 2.5 0.31 0.31 <0.16 <0.16 <0.16 <0.16 0.16 1 64 13
Bifidobacterium animalis subsp. lactis 0.16 1.87 <0.16 <0.16 <0.16 <0.16 <0.16 <0.16 4 8 <0.06 0.12
B. subtilis
IP 5832
2.5 2.5 0.62 0.62 0.31 0.31 0.31 0.62 <0.06 <0.06 8 16

MIC = minimum inhibitory concentration; MMC = minimum microbicidal concentration.

a

Data are given as mg/mL for plant extract and μg/mL for antibiotics.