TABLE 3.

Oxidation of PAHs by WT P450 BM-3 and mutants

Substrate	Substrate oxidation ratea
	WT	F87V	F87V/L188Q	A74G/F87V/L188Q
Naphthalene	0.76	111	115	160
Fluorene	0.014	2.8	22.7	52.8
Acenaphthene	0.0028	2.2	76.2	109
Acenaphthylene	0.12	71.3	149	287
9-Methylanthracene	0.0019	0.71	9.2	21.8

^aProduct oxidation rates were measured in units of nanomoles of product produced per nanomole of P450 per minute. Three independent experiments were done for each measurement.