Table 3.
List of top nodes obtained from Down-regulated PPI network
| Serial number | Symbol | Name | Degree | Betweenness Centrality | Closeness Centrality |
|---|---|---|---|---|---|
| 1 | ADIPOQ | Adiponectin | 4 | 0.691176 | 0.425 |
| 2 | FABP4 | Fatty acid binding protein 4 | 4 | 0.279412 | 0.377778 |
| 3 | PTGS2 | Prostaglandin endoperoxide synthase 2 | 4 | 0.330882 | 0.34 |
| 4 | GNG4 | Guanine nucleotide binding protein subunit 4 | 4 | 0.321429 | 0.533333 |
| 5 | TTN | Titin | 6 | 0.153846 | 0.565217 |
| 6 | CD36 | Platelet glycoprotein 4 | 5 | 0.308824 | 0.314815 |
| 7 | DMD | Dystrophin | 6 | 0.384615 | 0.619048 |
| 8 | MYL2 | Myosin regulatory light chain 2 | 5 | 0 | 0.541667 |
| 9 | TNNC1 | Troponin C1 | 5 | 0 | 0.541667 |
| 10 | MYL1 | Myosin regulatory light chain 1 | 6 | 0.051282 | 0.565217 |
| 11 | NEB | Nebulin | 8 | 0.461538 | 0.65 |
| 12 | SAA1 | Serum amyloid A1 | 4 | 0.321429 | 0.533333 |