Table 10: Intraocular pressure adjusted by central corneal thickness.
Intraocular pressure measurements adjusted by central corneal thickness, using five different formulas, in patients with glaucomatous optic neuropathy and patients with ocular hypertension.
| Unadjusted analysis | Adjusting for age, sex, race (white vs. non-white), and smoking history | ||||||||
|---|---|---|---|---|---|---|---|---|---|
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| Association between metabolic syndrome and: | N | Median (minimum, maximum) or No. (%) for the given group | N | Association measure | Estimate (95% CI) | P-value | Estimate (95% CI) | P-value | |
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| No Metabolic Syndrome | Metabolic Syndrome | ||||||||
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| Glaucomatous optic neuropathy | |||||||||
| CCT adjusted IOP mean (5 mmHg)36 | 301 | 12.2 (1.5, 24.3) | 1825 | 11.7 (−1.7, 58.4) | Odds ratio | 0.88 (0.77, 1.01) | 0.07 | 1.02 (0.87, 1.19) | 0.84 |
| CCT adjusted IOP mean both eyes (5 mmHg)39 | 301 | 13.8 (5.2, 26.9) | 1825 | 13.5 (2.8, 61.7) | Odds ratio | 0.92 (0.79, 1.07) | 0.29 | 1.15 (0.96, 1.38) | 0.14 |
| CCT adjusted IOP mean both eyes (5 mmHg)35 | 301 | 13.6 (4.2, 26.0) | 1825 | 13.3 (1.9, 60.6) | Odds ratio | 0.89 (0.77, 1.03) | 0.11 | 1.07 (0.90, 1.27) | 0.48 |
| CCT adjusted IOP mean both eyes (5 mmHg)37 | 301 | 14.4 (5.4, 27.0) | 1825 | 14.0 (2.8, 61.6) | Odds ratio | 0.89 (0.77, 1.04) | 0.14 | 1.09 (0.91, 1.30) | 0.36 |
| CCT adjusted IOP mean both eyes (5 mmHg)38 | 301 | 15.5 (5.8, 28.3) | 1825 | 15.1 (3.2, 62.5) | Odds ratio | 0.91 (0.79, 1.05) | 0.18 | 1.10 (0.93, 1.30) | 0.28 |
| Ocular hypertension | |||||||||
| CCT adjusted IOP mean both eyes (5 mmHg)36 | 95 | 13.5 (2.7, 30.2) | 489 | 13.8 (2.0, 36.3) | Odds ratio | 1.01 (0.80, 1.28) | 0.95 | 1.09 (0.83, 1.41) | 0.54 |
| CCT adjusted IOP mean both eyes (5 mmHg)39 | 95 | 16.0 (6.2, 28.3) | 489 | 16.8 (5.8, 35.3) | Odds ratio | 1.08 (0.83, 1.42) | 0.56 | 1.30 (0.95, 1.77) | 0.10 |
| CCT adjusted IOP mean both eyes (5 mmHg)35 | 95 | 15.3 (4.9, 30.1) | 489 | 15.9 (4.8, 36.2) | Odds ratio | 1.04 (0.80, 1.34) | 0.79 | 1.17 (0.87, 1.55) | 0.30 |
| CCT adjusted IOP mean both eyes (5 mmHg)37 | 95 | 16.2 (5.9, 30.4) | 489 | 16.8 (5.7, 36.4) | Odds ratio | 1.05 (0.81, 1.36) | 0.73 | 1.20 (0.89, 1.61) | 0.23 |
| CCT adjusted IOP mean both eyes (5 mmHg)38 | 95 | 17.5 (7.4, 35.5) | 489 | 18.0 (7.0, 43.4) | Odds ratio | 1.03 (0.80, 1.32) | 0.83 | 1.16 (0.87, 1.55) | 0.30 |
CI=confidence interval. Logistic regression model.