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. 2016 Jul 30;24(4):703–715. doi: 10.1016/j.jfda.2016.06.009

Table 1.

Measurement results of caffeine RM purity %.

Analyte HPLC-DAD (M1) UV/Vis spectrophotometer (M2)
Caffeine 99.905 99.860
99.909 99.790
99.940 99.905
99.854 99.810
99.899 99.928
99.901 99.714
99.872 99.827
99.902 99.812
99.971 99.887
99.920 99.886
99.900 99.730
99.868 99.842
99.961 99.800
99.914 99.877
99.904 99.764
99.866 99.915
99.970 99.753
99.857 99.755
99.882 99.908
99.869 99.880
Mean 99.903 99.832
SD ±0.036 ±0.066

HPLC-DAD = high-performance liquid chromatography coupled with diode array detection; M1 = Method 1; M2 = Method 2; RM = reference material; SD = standard deviation; Vis = visible.