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. 2022 Jul 29;8:89. doi: 10.1038/s41523-022-00455-5

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© The Author(s) 2022

Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/.

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Fig. 1 — The flow chart presents the number of patients included and the number of faecal samples collected by those patients during the study period. Multiple patients who did not collect a faecal sample at T2 were able to collect a faecal sample at T3. In total, 44 patients collected 153 faecal samples at four-time points. 28 participants provided all four samples. The total group is presented in the middle. On the left and right sides, the total group is subdivided into neoadjuvant and adjuvant groups.