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. 2022 Jul 29;12:12996. doi: 10.1038/s41598-022-16631-3

Table 2.

Multivariate Cox proportional hazard models for the association between concomitant PTA at the time of PCI and clinical outcomes.

Clinical outcomes Before PSM After PSM
Events Models* Events Models*
N = 279 N = 6284 HR (95% CI) P value N = 279 N = 1385 HR (95% CI) P value
Death 73 (26.2) 919 (14.6) 1.69 (1.32–2.15)  < 0.001 73 (26.2) 273 (19.7) 1.52 (1.17–1.98) 0.002
CV death 21 (7.5) 283 (4.5) 1.54 (0.99–2.42) 0.058 21 (7.5) 69 (5.0) 1.59 (0.97–2.59) 0.065
MACEs 79 (28.3) 1611 (25.6) 1.11 (0.89–1.40) 0.358 79 (28.3) 393 (28.4) 1.00 (0.78–1.27) 0.969
Myocardial infarction 13 (4.7) 414 (6.6) 0.87 (0.50–1.52) 0.625 13 (4.7) 80 (5.8) 0.85 (0.47–1.53) 0.591
Revascularization 49 (17.6) 962 (15.3) 1.25 (0.93–1.66) 0.136 49 (17.6) 237 (17.1) 1.09 (0.80–1.48) 0.594
Stroke 16 (5.7) 344 (5.5) 1.09 (0.66–1.81) 0.727 16 (5.7) 101 (7.3) 0.88 (0.52–1.50) 0.639
Any bleeding 9 (3.2) 209 (3.3) 0.97 (0.50–1.89) 0.920 9 (3.2) 49 (3.5) 0.91 (0.44–1.85) 0.787
ESRD 28 (10.0) 206 (3.3) 2.05 (1.37–3.06)  < 0.001 28 (10.0) 93 (6.7) 1.60 (1.05–2.45) 0.029
Amputation 20 (7.2) 108 (1.7) 3.81 (2.36–6.16)  < 0.001 20 (7.2) 34 (2.5) 3.41(1.96–5.92)  < 0.001
PTA after discharge 68 (24.4) 168 (2.7) 9.27 (6.93–12.4)  < 0.001 68 (24.4) 70 (5.1) 5.94 (4.25–8.30)  < 0.001

PSM, propensity score matching; PCI, percutaneous coronary intervention; PTA, Percutaneous transluminal angioplasty; CV cardiovascular; MACE, major adverse cardiovascular events; ESRD, endstage renal disease; HR, hazard ratio; CI, confidence interval.

*The multivariate model includes age, sex, BMI, waist circumference, MI at index admission, number of coronary stents used, income ≥ median, prior bleeding events, MI, PAD, stroke, diabetes, hypertension, peptic ulcer, DAPT duration and statin use as covariates. The model was reduced using a backward selection method (cutoff criterion, p > 0.1).