Table 3.

Univariate and multivariate analysis with hazard ratio (HR) and confidence interval (CI) for the development of new digital ulcers in SSc patients with increased resistin level

	Univariate analysis		Multivariate analysis
	HR (CI)	p	HR (CI)	p
Resistin	1.094 (1.035–1.157)	0.001	1.078 (1.014–1.145)	0.016
Nailfold capillaroscopic pattern (early)	0.205 (0.063–0.674)	0.009	0.381 (0.108–1.345)	0.134
SSc subset	1.915 (0.914–4.010)	0.085	–	–
SSc-specific autoantibodies	0.495 (0.224–1.096)	0.222	–	–
Disease duration	0.996 (0.936–1.061)	0.905	–	–
mRSS	1.077 (1.022–1.134)	0.006	1.011 (0.933–1.095)	0.789
DAI	1.215 (1.079–1.369)	0.001	1.070 (0.807–1.420)	0.637
DSS	1.152 (1.058–1.253)	0.001	1.074 (0.872–1.323)	0.502

The median value of resistin (ng/ml) is higher (p=0019) in SSc patients with new digital ulcers than in SSc patients without new digital ulcers

SSc systemic sclerosis, mRSS modified Rodnan skin score, DAI disease activity index, DSS disease severity scale