Fig. 1.

CDF plot of the change in ADCOMS score from baseline to month 12 by CDR-SOB for MCI patients. The dotted line indicates the proposed ADCOMS threshold for meaningful change for MCI (0.05). ADCOMS Alzheimer’s Disease Composite Score, CDF cumulative density function, CDR-SOB Clinical Dementia Rating Scale Sum of Boxes, MCI mild cognitive impairment