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. 2022 Jul 29;13:4395. doi: 10.1038/s41467-022-32127-0

Fig. 4. GBP1 peptide induces membrane disruption, expulsion of cytoplasmic and membranous content from F. novicida.

Fig. 4

a Scanning electron microscopy and (b) transmission electron microscopy analysis of the morphology of F. novicida 12 h after treatment with solvent control, 100 μg/mL of GBP128–67 or WLBU2. c Negative-stain transmission electron microscopy analysis of F. novicida 12 h after treatment with solvent control, 100 μg/mL of GBP128–67 or WLBU2. Scale bars, 200 nm (a), 500 nm (b) and 1 μm (c). Orange arrow heads indicate bacteria with disrupted cell membrane. Data are representative of three independent experiments (ac).