Table 1. Top eight key proteins in PPI network.
| DE mRNAs | Express | Degree | Pathways |
|---|---|---|---|
| GRIA1 | Down | 5 | cAMP signaling pathway |
| MMP9 | Up | 5 | Lipid and atherosclerosis Transcriptional misregulation in cancer |
| GRM5 | Up | 4 | Phospholipase D signaling pathway Calcium signaling pathway |
| HIST1H2AI | Up | 4 | Necroptosis Neutrophil extracellular trap formation |
| HIST1H2AM | Up | 4 | Necroptosis Neutrophil extracellular trap formation |
| HIST1H3J | Up | 4 | Transcriptional misregulation in cancer Neutrophil extracellular trap formation |
| HIST2H3A | Up | 4 | Transcriptional misregulation in cancer Neutrophil extracellular trap formation |
| HIST2H3C | Up | 4 | Transcriptional misregulation in cancer Neutrophil extracellular trap formation |