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. 2022 Jul 30;19:88. doi: 10.1186/s12954-022-00666-w

Table 3.

Current and lifetime patterns of cannabis use

Characteristic Prescribed only Prescribed and illicit Illicit only Total Comparisons estimate (95% CI)
Cannabis use before medical use, categorical non-binary, n (%)
Never used cannabis before medical use 126/186 (68%)a 63/320 (20%)bc 195/895 (22%)bc 384/1401 (27%) PO – P + I: 8.6 (4.5, 16.4)
PO – IO: 7.5 (4.4, 13.0)
Used ‘recreationally’ but had ≥ 1 year break before medical use 52/186 (28%)ab 123/320 (38%)abc 382/895 (43%)bc 557/1401 (40%) PO – IO: 0.5 (0.3, 0.9)
PO – P + I: 0.1 (0.0, 0.2)
Was using recreationally when started using medically 8/186 (4.3%)a 134/320 (42%)bc 318/895 (36%)bc 460/1401 (33%) PO – IO: 0.1 (0.0, 0.3)
Age first tried cannabis for any reason, numeric, (N = 1405)
Mean (SD) 33.2 (21.5)a 20.1 (10.7)bc 21.7 (13.8)bc 22.9 (15.0) PO – P + I: 13.2 (10.0, 16.3)
Median (IQR) 21 (16, 54) 16 (15, 20) 17 (15, 20) 17 (15, 21) PO – IO: 11.5 (8.7, 14.3)
Age first regular cannabis use any reason, numeric, (N = 1405)
Mean (SD) 35.4 (23.7)a 27.0 (15.1)bc 28.4 (17.3)bc 29.0 (18.0) PO – P + I: 8.4 (4.5, 12.4)
Median (IQR) 33 (18, 56) 22 (18, 33) 23 (18, 38) 24 (18, 39) PO – IO: 11.5 (3.5, 10.4)
Age first regular cannabis use for medical reason, numeric, (N = 1402)
Mean (SD) 41.3 (22.6)a 36.1 (14.7)bc 35.5 (18.2)bc 36.4 (18.2) PO – P + I: 5.2 (1.2, 9.2)
Median (IQR) 46 (28, 59) 35 (26, 45) 35 (23, 49) 35 (24, 50) PO – IO: 5.8 (2.3, 9.4)
Never used cannabis regularly for any reason, binary categorical, n (%) 32/187 (17%)a 13/322 (4%)bc 63/896 (7%)bc 108/1405 (8%) PO – P + I: 4.9 (2.2, 11.0)
PO – IO: 2.7 (1.6, 4.7)
Number of days in previous 28 used cannabis for any reason, numeric, (N = 1403)
Mean (SD) 21.8 (10.0)a 24.9 (6.7)bc 20.2 (10.2)bc 21.5 (9.7) PO – P + I: -3.1 (-5.2, -1.0)
Median (IQR) 28 (15, 28) 28 (12, 28) 28 (12, 28) 28 (15, 28) P + I – IO: 4.7 (3.2, 6.2)
Number of days in previous 28 used cannabis for medical reasons, numeric, (N = 1402)
Mean (SD) 21.3 (10.2)a 23.8 (8.0)b 18.7 (10.8)c 20.2 (10.4) PO – P + I: -2.5 (-4.7, -0.2)
PO – IO: 2.7 (0.7, 4.6)
Median (IQR) 28 (14, 28) 28 (24, 28) 25 (7, 28) 28 (12, 28) P + I – IO: 5.1 (3.6, 6.7)
Estimated proportion of cannabis use for medical reasons, numeric, Mean (SD), (N = 1392) 96.1 (14.2)a 91.9 (14.8)b 84.6 (21.4)c 87.8 (19.7) PO – P + I: 4.2 (0.0, 8.5)
PO – IO: 11.5 (7.8, 15.2)
P + I – IO: 7.2 (4.2, 10.2)
100% of cannabis use for medical reasons, binary categorical, n (%) 146/186 (79%)a 177/322 (55%)b 378/884 (43%)c 701/1392 (50%) PO – P + I: 3.0 (1.8, 4.9)
PO – IO: 4.9 (3.1, 7.6)
P + I – IO: 1.6 (1.2, 2.2)
Weekly cost of medical cannabis, numeric, (N = 1395)
Mean (SD) $79.2 ($61.6)a $114.0 ($77.4)b $58.6 ($65.4)c $74.0 ($71.6) PO – P + I: -35.5 (-49.7, -19.6)
PO – IO: 20.6 (7.4, 33.7)
Median (IQR) $60 ($35, $100) $100 ($50, $155) $40 ($7, $100) $40 ($7, $100) P + I – IO: 55.2 (44.6, 65.8)
Weekly cost of medical cannabis with respondents who did not pay excluded, numeric, (N = 1405)
Mean (SD) $81.4 ($61.0)ac $118.0 ($76.0)ab $73.2 ($65.4)ac $85.9 ($70.2) PO – P + I: -36.5 (-51.7, -21.3)
Median (IQR) $65 ($40, $100) $100 ($50, $170) $100 ($50, $155) $50 ($25, $100) P + I – IO: 44.7 (33.7, 55.7)

Superscript letters a–c indicate statistically significant between-group differences: Pairs of columns that do not share letters are significantly different from each other (p < 0.05). Missing values excluded from denominator when calculating percentages. Some percentages may not total 100% due to rounding. Letters a–c indicate statistically significant between-group differences. Columns that share letters are NOT significantly different. Median (IQR) reported for count variables only. IQR = Interquartile range. For each outcome, pairwise comparisons were made for all three groups: PO – P + I, PO-IO, and P + I – IO. Estimates are unstandardised effects size for numeric variables and odds ratios for categorical or ordinal variables. Only significant comparisons reported