Table 2.
Medication usage
| Medication | Total (%) | New MC (%) | MC Registry (%) | p-vala | MC (%) | No MC (%) | p-valb |
|---|---|---|---|---|---|---|---|
| Any Dose Aspirin | 42 (21.21) | 6 (28.57) | 19 (32.20) | 0.77 | 25 (31.25) | 17 (14.41) | < 0.01 |
| Other NSAIDs | 56 (28.28) | 9 (42.86) | 23 (39.65) | 0.80 | 32 (40.51) | 24 (20.34) | < 0.01 |
| Any Aspirin or NSAIDs | 77 (38.89) | 11 (52.38) | 32 (54.24) | 0.88 | 43 (53.75) | 34 (28.81) | < 0.01 |
| PPIs | 48 (24.24) | 4 (19.05) | 14 (23.73) | 0.66 | 18 (22.50) | 30 (25.42) | 0.64 |
| H2RAs | 10 (5.05) | 1 (4.76) | 5 (8.47) | 0.59 | 6 (7.50) | 4 (3.39) | 0.20 |
| SSRIs | 57 (28.79) | 6 (28.57) | 21 (35.59) | 0.56 | 27 (33.75) | 30 (25.42) | 0.20 |
| Statins | 54 (27.27) | 5 (23.81) | 17 (28.81) | 0.66 | 22 (27.50) | 32 (27.12) | 0.95 |
| ACE-Is | 18 (9.09) | 1 (4.76) | 2 (3.38) | 1.00 | 3 (3.75) | 15 (12.71) | 0.03 |
| ARBs | 16 (8.08) | 2 (15.38) | 3 (5.08) | 0.21 | 5 (6.94) | 11 (11.11) | 0.36 |
Medication use was compared between sources of microscopic colitis (MC) patients (p-vala), and between MC and no MC (p-valb) utilizing univariate statistics. NSAIDs: non-steroidal anti-inflammatory drugs, PPIs: proton pump inhibitors, H2RAs: histamine-2 receptor antagonists, SSRIs: selective serotonin reuptake inhibitors, ACE-Is: angiotensin converting enzyme inhibitors, ARBs: angiotensin receptor blockers