Table 4.

Multivariate regression analysis

Medication	Odds ratio (95% confidence interval)	p-val
Any dose aspirin	2.65 (1.28–5.64)	0.01
Other NSAIDs	2.71 (1.42–5.28)	< 0.01
Any aspirin or NSAIDs	3.04 (1.65–5.69)	< 0.01
PPIs	0.69 (0.34–1.39)	0.31
H2RAs	1.94 (0.52–7.95)	0.33
SSRIs	1.22 (0.64–2.33)	0.54
Statins	0.83 (0.41–1.68)	0.61
ACE-Is	0.17 (0.04–0.57)	< 0.01
ARBs	0.43 (0.12–1.35)	0.16

Multivariate binomial logistic regressions were utilized to control for the effects of age and gender on the association between each medication and microscopic colitis diagnosis. NSAIDs: non-steroidal anti-inflammatory drugs, PPIs: proton pump inhibitors, H2RAs: histamine-2 receptor antagonists, SSRIs: selective serotonin reuptake inhibitors, ACE-Is: angiotensin converting enzyme inhibitors, ARBs: angiotensin receptor blockers