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. 2022 Jul 30;20:341. doi: 10.1186/s12967-022-03540-2

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© The Author(s) 2022

Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated in a credit line to the data.

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Fig. 9 — The suppression of VEGFB gene stimulated the SREBP1/Scd1 signal pathway of lipid synthesis. A Western blot of SREBP1 and Scd1 in NAFLD mice model were analyzed. B Protein level of SREBP1 in NAFLD mice model. C Protein level of Scd1 in NAFLD mice model. D Western blot of SREBP1 and Scd1 in NAFLD cell model were analyzed. E Protein level of SREBP1 in NAFLD cell model. F Protein level of Scd1 in NAFLD cell model. G mRNA level of ACC1 and FAS in NAFLD mice model. H mRNA level of ACC1 and FAS in NAFLD cell model. N = 6 cases per group. B, C, G * indicates vs. SD, p < 0.05; # indicates vs. HFD, p < 0.05; E, F, H * indicates vs. NC, p < 0.05